In game-changer, Israeli researchers find Alzheimer’s markers 20 years before onset

Israeli researchers from the Hebrew University, led by Prof. Naomi Habib, have identified a unique cellular pathway in the brain that indicates markers for Alzheimer's disease up to 20 years before symptoms appear. Using a large data set from 437 aging brains, they mapped 1.65 million brain cells and developed an innovative algorithm, BEYOND, to predict whether an individual is on a path to healthier aging or Alzheimer’s. This discovery, published in Nature, identifies specific brain cells involved in early Alzheimer’s, offering hope for early intervention and a potential cure. The research highlights the importance of lifestyle choices in preventing Alzheimer’s, alongside genetic factors. Habib is also advocating for community awareness on healthy aging practices to lower risks associated with the disease.